VWF and Thrombocytopenia: Thus, “DIC” has been newly defined as EA-VMTD, which explains not only microvascular microthrombosis (i.e., VMTD), but also confirms the molecular changes associated with the disease (i.e., thrombocytopenia, increased activity of FVIII, and overexpression of ULVWF/VWF antigen) [5,6,8,20].