In the acute cystitis group, the cell profiles of p-CREB-IR were 31.3 ± 4.42 (L1), 32 ± 8.85 (L2), 28.79 ± 5.86 (L3), 20.17 ± 6.05 (L4), 25.64 ± 7.26 (L5), 29.14 ± 6.59 (L6), and 36 ± 8.49 (S1). This evidence concerns the gene CREB1 and cystitis.