In breast cancer, curcumin is shown to suppress the spread of cancer cells to other parts of the body via blocking receptor activator of NF-κB ligand, modulating histone deacetylases (HDAC), histone acetyltransferases (HAT), DNA Methyltransferase 1 (DNMT1), and microRNAs in various breast cancer cells [31,32,33]. The gene discussed is DNMT1; the disease is breast cancer.