BDNF and neurodegenerative disease: It is possible to guide cells into the neural differentiation pathway due to the overexpression of Bcl-XL/BDNF The protocol proposed as a result of these studies can be further investigated in in vivo experiments on neurodegenerative diseases in various animal models because, in addition to the gene overexpression, the ultimate role that determines the direction of differentiation is played by the brain’s microenvironment.