The optimal minimum collectrin cut-off level to distinguish between AKI and non-AKI is 1606 [95% CI 1258 to 1954] pg/mL, with a sensitivity and specificity of the assay of 0.74 and 0.70 and an AUC of 0.75 [95% CI 0.67 to 0.82; p < 0.01] (Figure 2). This evidence concerns the gene CLTRN and acute kidney injury.