OPN1SW and bone cancer: Consistent with the in vitro study, inhibiting miR-155-5p restored the expression of Sgk3 suppressed in the bone cancer pain rats assayed using RT-qPCR (multiple comparisons: adjusted p = 0.0128, BCP + NC vs. sham + NC; adjusted p = 0.0238, BCP + NC vs. BCP + sponge; Figure 6C) and Western blot (multiple comparisons: adjusted p = 0.0137, BCP + NC vs. sham + NC; adjusted p = 0.0018, BCP + NC vs. BCP + sponge; Figure 6D), indicating the regulatory effect of miR-155-5p.