CTSC and COVID-19: A similar approach using asymptomatic individuals as controls was used in a GWAS on the Chinese population that revealed significant associations at the chromosome loci, 11q23.3 and 11q14.2 with severe COVID-19 and noted significant expression quantitative trail locus (eQTL) associations for RNA Exonuclease 2 (REXO2), C11orf71, Nicotinamide N-Methyltransferase (NNMT1), and Cell Adhesion Molecule 1 Precursor (CADM1) at 11q23.3 and Cathepsin C (CTSC) at 11q14.2 [30].