A retrospective immunohistochemical study of TAM in biopsies collected from patients with oral cavity squamous cell carcinoma (OSCC) revealed high expression levels of anti-inflammatory IL-10 and TGF-β cytokines characteristic of M2-like phenotypes [64], along with elevated levels of soluble IL-10 and TGF-β in OSCC compared with matching biopsies of normal oral mucosa [64]. Here, IL10 is linked to oral cavity squamous cell carcinoma.