MAPT and Alzheimer disease: Current trends aim toward the use of “smart drugs” [37,59,76], with complementary and adjuvant therapies, using phytopharmaceuticals with antioxidant properties of positive modulation on neuroprotection, covering a wide spectrum of targets that are triggered in AD, such as energy metabolism of the mitochondria, modulation of genes related to the amyloidogenic pathway, and interaction on Tau hyperphosphorylation, among others.