POU5F1 and Parkinson disease: Chen et al., 2021 demonstrated that an iPSCs line could be developed from PBMCs of a 32-year-old PD patient with homozygous mutation of c.189dupA in PARK7 (FJMUUHi001) by reprogramming five factors, OCT3/4, SOX2, c-MYC, KLF4, and BCL-XL.