TG and major depressive disorder: However, a recent network meta-analysis recommended that for patients with depression who are refractory to treatment with an initial antidepressant, the augmentation of antidepressant therapy with lower doses of an AAP (aripiprazole, brexpiprazole, cariprazine, olanzapine, quetiapine, or risperidone), dopamine compounds (lisdexamfetamine and modafinil), lithium, and thyroid hormone (liothyronine and T4) is feasible from the viewpoints of safety and efficacy [97].