Here, were noted the results as follows: LVI (R = 0.2181, p = 0.069), expression of vimentin (R = 0.8199, p = 0.000), tumor budding (R = 0.6407, p = 0.000), and lack of E-cadherin (R = 0.6948, p = 0.000). This evidence concerns the gene CDH1 and neoplasm.