CD30+ lymphomas comprise Hodgkin lymphomas (HL), but also a variety of T-cell lymphoma types including angioimmunoblastic T-cell lymphomas (AITL), anaplastic large-cell T-cell lymphomas (ALCL), Sézary syndrome, peripheral T-cell non-Hodgkin lymphoma (T-NHL) NOS, and numerous rare malignant T-cell lymphoma entities. The gene discussed is TNFRSF8; the disease is T-cell non-Hodgkin lymphoma.