We found significant main effects for gender (p = 0.001) and depression (p = 0.039) and additionally observed significant interactions for modification with the number of medications (p = 0.001) and depression (p = 0.017), as well as for missing knowledge with number of medications (p = 0.013) and MoCA (p < 0.001). This evidence concerns the gene DOCK3 and depressive disorder.