IL4 and neoplasm: Without WGP, the mitochondrial activity in M1 (LPS-induced macrophages) was lower than in the M0 control, while the activity in M2 (IL-4 activation) and TAM (supernatant tumor induction) were not significantly different to the M0 control, as indicated by the oxygen consumption rate (OCR) (Figure 6A upper) and the respiratory parameters (maximal respiration and respiratory reserve) (Figure 6E).