LCN2 and neoplasm: Given our findings on the distinct clustering of Gprc5a−/−; Lcn2−/− gut microbiome compared to its Gprc5a−/− counterpart (Figure 4D) and given the unique genera we unraveled by SIMPER and indicator analyses in Gprc5a−/−; Lcn2−/− mice, we sought to compare differential microbial composition among the two animal genotypes in an attempt to understand the increased tumor burden associated with the loss of Lcn2.