To substantiate the drop in CD4+CD25+CD127low Treg and CD4+ Tcon repertoire diversity in GVHD, which suggests the expansion of GVHD specific clonotypes, we visualized the repertoire proportion of individual clones comparing four representative samples for aGVHD, c/oGVHD, noGVHD and HCs (Figure 4A,B). The gene discussed is CD4; the disease is graft versus host disease.