GDF15 and breast cancer: Given the above analysis in the GSE59732 and GSE59733 dataset, five intersecting DEGs (GDF15, IFIT1, CDKN1A, FAS, BTG2) were screened out among 30 DEGs in the MCF-7 cell line, 280 DEGs in the ZR751 cell line and 585 DEGs in tumor samples of breast cancer patients (Figure 2C).