Data suggest that significantly higher percentages of CD4+/CTLA4 and CD8+/CTLA4 T lymphocytes have been observed in patients with endometriosis and intraoperative adhesions, implicating that there is a possible correlation between the ratio of CD8+ T/CD4+ T and endometriosis-related infertility [28]. The gene discussed is CTLA4; the disease is endometriosis.