Thus, the purpose of this study was to verify possible differences in immune-mediated inflammatory parameters, evaluated by the expression of toll-like receptors (TLRs), and oxidative stress [evaluated by nuclear factor kβ (NF-kβ)] in a group of newly diagnosed hypertensive patients with or without 1-h post-load hyperglycemia. The gene discussed is NFKB1; the disease is Hyperglycemia.