Nevertheless, the issue deserves careful consideration in view, for example, of the presence of vaccine mRNA and vaccine-induced S protein in axillary lymph nodes up to 60 days after both mRNA-1273 or BNT162b2 COVID-19 vaccines [9] as well as the occurrence of the S protein in circulating monocytes of vaccinated subjects with PASC-like symptoms many months after vaccination [11]. This evidence concerns the gene PROS1 and long COVID-19.