MAPT and Parkinson disease: For example, it was shown that in Alzheimer’s disease (AD), CNS-derived exosomes contain amyloidogenic proteins, such as hyperphosphorylated tau [76,77,78] and monomeric or oligomeric amyloid β-protein (Aβ) [79,80], while in Parkinson’s disease (PD), they can carry misfolded α-synuclein [81].