UCP1 and obesity due to melanocortin 4 receptor deficiency: This result does not seem to agree with the literature, since, although BAT has a greater resistance to inflammation than white adipose tissue, it is known that, in obesity, the secretion of proinflammatory cytokines seems to alter the thermogenic function of BAT with a reduction in the expression levels of UCP1 and other markers of thermogenesis [42].