NRGN and Alzheimer disease: Interestingly, we also found higher CSF Ng and α-Syn in AD than n-AD (Ng: AD = 388 (238–531) pg/mL vs. n-AD = 192.5 (85.2–295) pg/mL, p < 0.001; α-Syn: AD = 2756 (2226–3164) pg/mL vs. n-AD = 2265 (1293–2542) pg/mL, p = 0.031), with a small size effect (Ng: η2 = 0.242; α-Syn: η2 = 0.398).