APOE and Alzheimer disease: For this purpose, we stratified patients on the basis of pathological MMSE scores (i.e., <24); pathological values of the Aβ 42/40 ratio (i.e., <0.066), pTau (i.e., >61 pg/mL) and tTau (i.e., >416 pg/mL); and the presence/absence of the ApoE4 genotype (both in homo- and in heterozygosis) and AD-related PET pattern.