ROC analyses (Figure 2c,d) showed that the Ng levels were able to discriminate AD from n-AD patients (AUC = 0.768; C.I. 95% (0.682–0.853); p = 0.004), with a sensitivity of 68% and a specificity of 78%, while the AUC of α-Syn did not reach statistical significance (AUC = 0.689; C.I. 95% (0.514–0.804); p = 0.076). The gene discussed is NRGN; the disease is Alzheimer disease.