The therapeutic effect of TRP agonists on swallowing function has been recently studied; however, it is still not known which of these receptors (TRPV1, TRPA1, TRPM8) and agonists offers the best pharmacological profile to improve both the biomechanics and the neurophysiology of swallowing in patients with chronic OD. Here, TRPV1 is linked to osteochondritis dissecans.