Compared with those in normal controls, the expression levels of METTL14, RBM15, ZCCHC4, YTHDC1, YTHDF1, FMR1, IGF2BP2, and HNRNPA2B1 were higher in AD patients, while METTL3, METTL5, PCIF1, YTHDF2, FIF3H, and FTO were lower correspondingly. The gene discussed is METTL5; the disease is Alzheimer disease.