Anti-C5 treatment did not affect liver histology as the levels of steatosis (52 ± 3%) (macrovesicular (27 ± 2%) and microvesicular (26 ± 3%)) and lobular inflammation 3.1 ± 1.3 inflammatory aggregates/mm2) were all comparable to HFD+vehicle (Figure 4A–E). This evidence concerns the gene C5 and steatosis.