cg06646708 is framed by two 450K probes (cg18068140 and cg18232313) within the NHLRC1 upstream region, which were uniformly hypomethylated with elevated gene expression in lung tumor tissue from TCGA (lung adenocarcinoma (ADC): Figure 2B,C and squamous cell carcinoma (SCC): Supplementary Figure S2A,B. This evidence concerns the gene NHLRC1 and lung adenocarcinoma.