Alterations in Apo profiles, as the important structural component of lipoproteins (we did not examine HDL-C, LDL-C, or VLDL-TAG levels—a significant limitation of this study), may be associated with disturbances within the lipoprotein profile, which might be related to the occurrence of many metabolic disorders, and could be established an important factor in cardiovascular complications. This evidence concerns the gene AOPEP and metabolic disease.