APOH and hypertriglyceridemia: Increased levels of Apo-C3 and Apo-H induce inhibition of triacylglycerol-rich lipoprotein (TRL) lipolysis and impair the hepatic TRL clearance, which may result in hypertriglyceridemia and the formation of atherosclerotic plaques, thereby significantly increasing the risk of cardiovascular disorders [45,46].