The concentrations of IL-6 in the blood serum during onset demonstrated good sensitivity and specificity in predicting patients’ functional outcomes, both determined after discharge from hospital (cut-off point, IL-6 = 7.11 pg/mL, sensitivity = 88.6%, specificity = 83.3%, AUC = 0.887), during 90 days (cut-off point, IL-6 = 6.54 pg/mL, sensitivity = 77.3%, specificity = 93.3%, AUC = 0.918) as well as 1 year (cut-off point, IL-6 = 8.55 pg/mL, sensitivity = 95.2%, specificity = 100%, AUC = 0.992) since the stroke. Here, IL6 is linked to Stroke.