Thus, propolis and its components (fisetin, myricetin, quercetin, resveratrol, apigenin, genistein, cyanidin, daidzein, hesperetin, and naringenin), which are capable of inhibiting enzymes involved in glucose metabolism such as GLUT, hexokinase, or PKM2, could represent a valuable option in cancer treatment [82,407,408,409,410,411,412,413,414]. This evidence concerns the gene PKM and cancer.