In human hepatic cancer cells SK-HEP-1, kaempferol increased protein levels of LC3-II, p-AMPK, Atg 5, Atg 7, Atg 12, and Beclin-1 and suppressed protein levels of cyclin-dependent kinase 1 (CDK1), cyclin B, p-Akt, and p-mTOR, altogether resulting in G2/M cell cycle arrest and induction of autophagy [226,231]. The gene discussed is CDK1; the disease is liver cancer.