TGFB1 and eosinophilic esophagitis: It is induced by TGF-β1 and has increased expression in the basal epithelium of pediatric patients with active eosinophilic esophagitis (an allergen-mediated disease characterized by eosinophil recruitment to the esophagus [33]) and expression levels that correlate positively with subepithelial fibrosis [34].