The serum concentrations of EOTAXIN, GROα, IL-8, IP-10, MCP-1, MCP-3, MIG, MIP1α, MIP1β and RANTES were significantly elevated in both groups of severe COVID-19 patients compared to the healthy controls (surviving patients vs. controls: p = 0.001, p < 0.0001, p < 0.0001, p = 0.010, p < 0.0001, p = 0.012, p < 0.0001, p = 0.003, p < 0.0001 and p < 0.0001, respectively; non-surviving vs. controls: p = 0.009, p < 0.0001, p < 0.0001, p<0.0001, p < 0.0001, p < 0.0001, p < 0.0001, p = 0.001, p < 0.0001 and p = 0.012, respectively) (Figure 3A,B). This evidence concerns the gene CCL4 and COVID-19.