To further explore the effects of Keap1 and Keap1α on tumour growth, Keap1-Restored and Keap1α-Restored cells, alongside Keap1−/− (WT) cells, were, respectively, heterotransplanted into three groups, each including five immunodeficient nude mice, at their subcutaneous loci as indicated. This evidence concerns the gene KEAP1 and neoplasm.