ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: In addition, Naito’s group developed BCR-ABL degraders PROTAC 23 (Table 1) [54] and PROTAC 24 (Table 1) [53] called SNIPER (ABL), which induced the degradation of BCR-ABL protein in BCR-ABL positive CML cells and inhibited the growth of chronic myeloid leukemia K562 cells.