First, PHLDA1 was positively correlated with the infiltration levels of a variety of immunocompetent tumor-infiltrating cells, including Act CD4, CD56dim, and Act DC (Table 1, Supplementary Figure S4A), and 23 types of immune promoters, including IL6, NT5E, and TNFSF9 (Figure 4A). This evidence concerns the gene IL6 and neoplasm.