In contrast, PHLDA2 was negatively correlated with the infiltration levels of several immunocompetent tumor-infiltrating cells, including TemCD8, Th1, and NKT cells (Table 1, Supplementary Figure S4B), and PHLDA2 was negatively correlated with most immunomodulators (immune promoters, MHC molecules, chemokines, and chemokine receptors) in PAAD (Figure 4B–E). The gene discussed is HLA-C; the disease is pancreatic adenocarcinoma.