GPC1 is involved in the tumorigenesis of several tumor types, including PDAC, and several reports suggest a link between GPC1 and neurodegenerative diseases such as Alzheimer’s disease, prion disease, and Niemann–Pick-type C1 disease [18,38,59,60,82,83,84,85]. The gene discussed is GPC1; the disease is Niemann-Pick disease type C.