Among the human FDG studies, Ripa et al., in a randomized control trial of 102 patients with T2DM of a duration of 10–12 years, were not able to prove any changes in FDG uptake in the carotids and ascending aorta following a 26-week course of treatment with the insulin-releasing drug liraglutide. Here, INS is linked to type 2 diabetes mellitus.