HAVCR1 and infection: Specifically, TIM-1 has been shown to enhance a recombinant replication-competent vesicular stomatitis virus that encodes SARS-CoV-2 spike (rVSV/Spike) infection over a wide range of ACE2 concentrations [38], whereas a mutant of TIM-1 that does not bind to phosphatidylserine was unable to facilitate SARS-CoV-2 entry [39].