SLC5A2 and infection: Candida organisms are capable of colonizing the vaginal environment asymptomatically; however, several factors may contribute to the development of infection, including pregnancy, immunosuppression (HIV/AIDS or diabetes mellitus), sexual activity, hormonal fluctuations, smoking, obesity, and the use of sodium glucose cotransporter 2 (SGLT2) inhibitors, broad spectrum antibiotics, or oral contraceptives [4,5,6,7].