At the same time, the production of anti-tumor IFN-γ by γδ T cells is reduced; (2) hypercholesteremia induces higher levels of IL-17 in the serum and promotes tumor growth; (3) obesity disrupts IL-17-mediated regulation on intestinal microbiota, which results in glucose intolerance and insulin resistance, which are also linked to increased risk in cancer development. This evidence concerns the gene IL17A and neoplasm.