Similarly, fourteen genes are reported to cause LCA, encoded proteins which are involved in the development and physiology of the visual pathway such as CRB1 (photoreceptor morphogenesis), CRX (retinal development), MERTK (RPE phagocytosis), RDH12 (retinal reductase), LRAT (Lecithin Retinol Acyltransferase), RPE65 (vitamin A metabolism) RPGRIP1L (cilium formation) [10,11] NMNAT1 (protein multimerization) [12], GUCY2D (Guanylate Cyclase 2D) and AIPLI (phototransduction) [13]. This evidence concerns the gene LRAT and Leber congenital amaurosis.