Many studies employed the NGS as a technology in the detection of BRCA1/2 gene variants in various ethnic groups to implement the detection of gene variants using NGS in the routine line of diagnostics and may allow doctors to make more prompt and informed decisions about surgery or neo-adjuvant chemotherapy in breast cancer patients [35,36,37,38,39,40,41,42]. This evidence concerns the gene BRCA1 and breast cancer.