Given that neonatal puppies are very sensitive to hypoglycemia, it is possible that EHBP1L1−/− neonates are at increased risk for functional hypoglycemia that is secondary to the dysfunctional regulation of GLUT4 translocation and glucose uptake in the brain, musculature, and fat [49,50]. The gene discussed is EHBP1L1; the disease is Hypoglycemia.