An investigation of castration-sensitive PCa patients (n = 10), conducted by Afshar-Oromieh et al., indicated that continuous long-term ADT (defined by a mean duration of 7 months) significantly reduces the visibility of tumoral lesions on [68Ga]PSMA-11 PET/CT [21]; however, irrespective of complete or partial PSA response, PSMA uptake was increased in 13% of lesions. The gene discussed is FOLH1; the disease is posterior cortical atrophy.