Three Moroccan patients from two different families who presented a reduced visual acuity associated with typical clumped pigmentary retinal degeneration were described by Littink et al. One patient carried a homozygous missense variant (c.508C>A; p.Arg170Ser) in the NRL gene, whereas the same change was identified heterozygously in the two siblings of a second family, associated with a one base pair deletion (c.654del; p.Cys219ValfsTer4) on the other allele [19]. The gene discussed is NRL; the disease is Pigmentary retinopathy.