Agammaglobulinemia with other inherited pattern were also concluded: AR agammaglobulinemia was associated with mutations in several other genes such as IGHM, IGLL1, CD79A, CD79B, BLNK, PIK3R1, and TCF3 genes; AD-related agammaglobulinemia was also found with LRRC8A and TCF3 gene mutations [135]. The gene discussed is TCF3; the disease is Alzheimer disease.