There was no difference in BChE activity between patients with and without vvECMO on day 7 after ICU admission (critically ill COVID-19 patients without vvECMO support (n = 7): 1.237 U/l (843–1.634) vs. critically ill COVID-19 patients on vvECMO support (n = 38): 1.020 U/l (833–1.323)). This evidence concerns the gene BCHE and COVID-19.