The analysis revealed that TUBB might be involved in different pathways in ERα-positive and ERα-negative breast cancer, in which TUBB might be more involved in the activation of TSC/mTOR pathway in ERα-positive breast cancer as the genes that significantly correlate with TUBB in ERα-positive breast cancer were shown to be more involved in TSC/mTOR pathway compared to genes that correlate with TUBB in ERα-negative breast cancer. Here, TUBB is linked to breast carcinoma.