Recently, hallmarks predisposing to severe illness have been identified that describe the main alterations occurring in the course of the disease [41]; among them, high circulating levels of the cytokine IL-6 and the chemokines MCP-1 and IP-10 have been identified as reliable markers to predict COVID-19 severity and survival [42,43,44,45]. This evidence concerns the gene CXCL10 and COVID-19.