On the other hand, the inhibition of JAK1/2 has been postulated to produce an impairment of interferon-mediated antiviral response, with a potential facilitating effect on the evolution of SARS-CoV-2 infection [39], and to an increased susceptibility to other viral infections, as described in patients with rheumatoid arthritis [40]. Here, JAK1 is linked to rheumatoid arthritis.